ad. 28. Can chorionic villus sampling cause defects in the development of fetal limbs?

Chorionic villus sampling carried out after 11 weeks, does not influence the development of limbs and does not cause any defects. In very old reports concerning chorionic villus sampling, when it was performed very early, i.e. at 8 or 9 weeks, defects in limbs development in some individual cases were detected. Therefore, nowadays, early chorionic villus sampling is not performed.

The method of collecting samples ensures that the amniotic sac is protected and thus it means no defects in limbs, which are fully developed after 11 weeks of gestation.